Basic Information
VIS ID
TVIS30015886
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
192508579/191643853 (Hg38)
End
192508710/191643853 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/2510742; hsa-mir-1244-1/Downstream/15139381;
Nearest TSS
ENST00000437798/Upstream/232788; ENST00000491331/Downstream/34215;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/397639, chr2-CpG: 88/Downstream/33994
Upstream sequence
gattgttgtgagatttaaatacgtcactacaaagtgtttagtatagtgctgggcaaatggcaagccctcatttatattagttatgttcaccatttcttat
Downstream sequence
tcaagagCTAGGACTTGTGATTTATTACATATCTGTGTTTTCAGAGAAGACAACGGTCATTTTTATGACACTTTCTGGAATAATTCTAGAGTTTATCTTA
Target sequence
aaccccatgacgcaggcaccattattataatcatgttacaggagaggaaactgattatcagagaggatagcagcttgcctaatgttatccagcaagtaagtgactgggattcctaggctgaccggtccaac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate