Basic Information
VIS ID
TVIS30015887
Fusion event
HIV-NABP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
192549900/191685174 (Hg38)
End
192550004/191685174 (Hg38)
Orient
+
Location type
Intronic
Target gene
NABP1
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-95-5p ; hsa-mir-106a-5p ; hsa-mir-124-5p ; hsa-mir-130a-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-595 ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-1297 ; hsa-mir-548t-5p ; hsa-mir-4295 ; hsa-mir-4255 ; hsa-mir-3666 ; hsa-mir-4465 ; hsa-mir-5697 ; hsa-mir-548az-5p ; hsa-mir-4253 ; hsa-mir-4632-5p ; hsa-mir-4761-3p ; hsa-mir-4436b-3p ; hsa-mir-6735-5p ; hsa-mir-6862-5p ; hsa-mir-6879-5p ; hsa-mir-7843-5p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-5692a ; hsa-mir-548n
Nearest miRNA
hsa-mir-10b/Upstream/2552063; hsa-mir-1244-1/Downstream/15098060;
Nearest TSS
ENST00000437798/Upstream/1669; ENST00000413304/Downstream/108251;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/6307, chr2-CpG: 34/Downstream/196784
Upstream sequence
actcctgacctcaaatgatccacctgcctcggcgtcctaaagtgctgggattacatacaggcgtgagccactgaacctggccAGCTCATGTTTTATTTGA
Downstream sequence
TTTGAGCCAAATTCCAATATTCACTATTTTGCCCTTTCTTTTTCTTTTATAGTGTAGGCAATGCATTTTTTTACTCTATTAATTTCTAATTTTGATGCCC
Target sequence
CTCGAAGGCTACATGTCTTGGCATTGCTGATCACATTGTGGGAAACGCTGCCTTTGCCTTTAAAAAGTTAGAATAACATTGTCTGTTTTGAGATATTAATCATA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate