VISDB Viral Integration Site DataBase

VIS ID

TVIS30015898

Fusion event

HIV-IKZF2 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr2

Cytoband

q34

Reference genome

Start

End

213978630/213113782 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-130b-5p ; hsa-mir-125b-5p ; hsa-mir-374a-5p ; hsa-mir-627-3p ; hsa-mir-633 ; hsa-mir-450b-5p ; hsa-mir-6805-5p ; hsa-mir-876-5p ; hsa-mir-1290 ; hsa-mir-3167 ; hsa-mir-5004-3p ; hsa-mir-506-5p ; hsa-mir-1260a ; hsa-mir-1260b ; hsa-mir-6083 ; hsa-mir-5096 ; hsa-mir-3926 ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-10b-3p ; hsa-mir-6869-5p ; hsa-mir-496 ; hsa-mir-942-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-376a-5p ; hsa-mir-3938 ; hsa-mir-6844 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-5588-3p ; hsa-mir-6832-3p ; hsa-mir-3156-3p ; hsa-mir-188-3p ; hsa-mir-1236-3p ; hsa-mir-877-3p ; hsa-mir-4301 ; hsa-mir-1306-5p ; hsa-mir-7850-5p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p

Nearest miRNA

hsa-mir-10b/Upstream/187446; hsa-mir-1244-1/Downstream/644285;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/280456, chr2-CpG: 39/Downstream/38244

Nearest cancer related gene

IKZF2(TSG, No orient, 0)

Upstream sequence

CCCTTATCTCTCTTTCTTCAGCTGTACCTATTGATACTTGGCACATACGTTTTTTCTAATTGTTTTAGGGAAGGAGTGGAGAGAGGTGTTTGTTTGTTTT

Downstream sequence

ACAAGGATGACAAGTGCTAGCAATGGCCAGAATGCCTATCTCCCACTGCAACTGCAATCCCAAACTCCTCCTAATATACCTGTAATAATCAGTTACGTCT

Target sequence

GTTTTAGCATGTTTCTAAATGTGCCTGGGATTATATTCTTAAAGTTGGCATCTATTGAGCAAGGAGGGGCAAGGATACACAAGTTTGACAGAAATAAAGGTAAATAGCTATTTTTATACTCATC