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TVIS30015900
Basic Information
VIS ID
TVIS30015900
Fusion event
HIV-ARPC2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
219101540/218236817 (Hg38)
End
219101318/218236817 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARPC2
miRNAs that regulate target gene
hsa-mir-149-5p
;
hsa-mir-93-5p
;
hsa-mir-92a-3p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-5006-5p
;
hsa-mir-3972
;
hsa-mir-1202
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-7162-5p
;
hsa-mir-516b-3p
;
hsa-mir-516a-3p
;
hsa-mir-3194-5p
;
hsa-mir-6878-3p
;
hsa-mir-640
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-3934-5p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-378a-5p
;
hsa-mir-3653-5p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-6131
;
hsa-mir-4755-3p
;
hsa-mir-3663-5p
;
hsa-mir-411-5p
;
hsa-mir-4775
;
hsa-mir-4735-5p
;
hsa-mir-6832-5p
;
hsa-mir-6872-3p
;
hsa-mir-590-3p
Nearest miRNA
hsa-mir-10b/Upstream/336189; hsa-mir-1244-1/Downstream/43308;
Nearest TSS
ENST00000437798/Upstream/1476;
ENST00000462034/Downstream/1902;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/19243
,
chr2-CpG: 58/Downstream/33247
Upstream sequence
ggaggcggatgttgtggtgagccgagatcatgccattgcactccagcctgggcaataagagtaaaactccatctcaaaaaaaaaaaaaTACAGATCTCAG
Downstream sequence
GAATGCTTTTGGGAAAAAATGAAATAGTAATGAGGTTTCAGATACTTAGAAGTGTGAAAGCCATACAGTTCTGGTGAAGTTATTCCCGTCAGTTGCCTAG
Target sequence
cagcatgaccaacatggagaaaccccgtctctactaaaagtacaaaattagccaggcctggtggcgcatgcctgtaatcccagctgcctaggaggctgaggcaggagaatcgcttgaacctgggaggcggatgttgtggtgagccgagatcatgccattgcactccagcctgggcaataagagtaaaactccatctcaaaaaaaaaaaaaTACAGATCTCAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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