Basic Information
VIS ID
TVIS30015907
Fusion event
HIV-FARP2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
242315100/241375685 (Hg38)
End
242315067/241375685 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2J
Target gene
FARP2
Nearest miRNA
hsa-mir-10b/Upstream/919596; hsa-mir-3133/Downstream/102220;
Nearest TSS
ENST00000437798/Upstream/2496; ENST00000467260/Downstream/11058;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/18899, chr2-CpG: 182/Downstream/131917
Upstream sequence
TTTACAATATTTAGAGCTTGTCAGTTTTAATAAATTGAGATTATGGTTTCAGTTAAATATAACCGTCATGTTTGGTATTTGAGATATCTGGCAGAGTTAC
Downstream sequence
CAGAAATTAAAGAACTTTTATCTGAAGCAAAAGAAAATGGTCTTGCATATTCTGAATATCCTGGGTTGGATGGGGTACtttttttttttaagagacagga
Target sequence
ATGTTTGGTATTTGAGATATCTGGCAGAGTTAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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