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TVIS30015937
Basic Information
VIS ID
TVIS30015937
Fusion event
HIV-NCOA3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
46206736/47577992 (Hg38)
End
46206917/47577992 (Hg38)
Orient
+
Location type
Intronic
Target gene
NCOA3
miRNAs that regulate target gene
hsa-mir-98-5p
;
hsa-mir-21-5p
;
hsa-mir-19b-3p
;
hsa-mir-18a-5p
;
hsa-mir-29b-3p
;
hsa-mir-17-5p
;
hsa-mir-33a-5p
;
hsa-mir-590-3p
;
hsa-mir-335-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-744-5p
;
hsa-mir-20a-5p
;
hsa-mir-548c-3p
;
hsa-mir-219a-1-3p
;
hsa-mir-571
;
hsa-mir-758-3p
;
hsa-mir-1252-3p
;
hsa-mir-6808-3p
;
hsa-mir-7973
;
hsa-mir-93-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-137
;
hsa-mir-126-5p
;
hsa-mir-378a-5p
;
hsa-mir-608
;
hsa-mir-1200
;
hsa-mir-302f
;
hsa-mir-3664-5p
;
hsa-mir-3941
;
hsa-mir-4641
;
hsa-mir-4651
;
hsa-mir-219b-3p
;
hsa-mir-4690-3p
;
hsa-mir-4731-5p
;
hsa-mir-4789-3p
;
hsa-mir-4795-3p
;
hsa-mir-5685
;
hsa-mir-6856-3p
;
hsa-mir-8485
;
hsa-let-7a-5p
;
hsa-let-7b-5p
;
hsa-let-7c-5p
;
hsa-let-7d-5p
;
hsa-let-7e-5p
;
hsa-let-7f-5p
;
hsa-mir-181a-5p
;
hsa-mir-181b-5p
;
hsa-mir-181c-5p
;
hsa-mir-214-3p
;
hsa-let-7g-5p
;
hsa-let-7i-5p
;
hsa-mir-342-5p
;
hsa-mir-181d-5p
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-761
;
hsa-mir-3619-5p
;
hsa-mir-3150b-3p
;
hsa-mir-3927-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4455
;
hsa-mir-4458
;
hsa-mir-4500
;
hsa-mir-4664-5p
;
hsa-mir-4689
;
hsa-mir-4722-5p
;
hsa-mir-4784
;
hsa-mir-6165
;
hsa-mir-6737-5p
;
hsa-mir-6747-5p
;
hsa-mir-6812-5p
;
hsa-mir-6819-5p
;
hsa-mir-6831-5p
;
hsa-mir-6858-5p
;
hsa-mir-7155-5p
;
hsa-mir-580-3p
;
hsa-mir-4324
;
hsa-mir-4251
;
hsa-mir-382-3p
;
hsa-mir-4495
;
hsa-mir-4803
;
hsa-mir-30e-5p
;
hsa-mir-30c-5p
;
hsa-mir-30b-5p
;
hsa-mir-30a-5p
;
hsa-mir-30d-5p
;
hsa-mir-4642
;
hsa-mir-488-5p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-5583-3p
;
hsa-mir-4517
;
hsa-mir-4796-3p
;
hsa-mir-6805-3p
;
hsa-mir-5691
;
hsa-mir-544b
;
hsa-mir-224-5p
;
hsa-mir-1294
;
hsa-mir-4316
;
hsa-mir-5589-5p
;
hsa-mir-4524b-3p
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-219a-2-3p
;
hsa-mir-17-3p
;
hsa-mir-20b-3p
;
hsa-mir-3529-5p
;
hsa-mir-379-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/410934; hsa-mir-1-1/Downstream/2285867;
Nearest TSS
ENST00000382410/Upstream/76051;
ENST00000490248/Downstream/44966;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/75679
,
chr20-CpG: 165/Downstream/207006
Nearest cancer related gene
NCOA3
(OG, No orient, 0)
Upstream sequence
CAGCTTGATTCTTTCTAGTATATATCACAAGATATGTGGTAATACCTGTCTTTATTTTACTAGACATGCATATGCTGTAATTTGAAATAATTCCTTGTCC
Downstream sequence
TTTTATATAACTTTATTATTATTAttttttaagacagagtcttgctctgttgcccaggctggagtgcagtggcgcgatctcagctcactgcaacctctgc
Target sequence
CCCACTCCCTTATCAAGAAGATTATAGCATTTAAAAAAGATTGTTATAAATGTCTTACCAATGTTCTCCTGGGAAGCAAATACATTTTTACTTAATTGAACATACAATAATGGACTAAGTAATGGGAAAAAAAAATTCTTAAACTGAGTTAAGTTTATATAGCTCAAAAAAAGTGGTACCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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