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TVIS30015945
Basic Information
VIS ID
TVIS30015945
Fusion event
HIV-NTSR1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
61365169/62733817 (Hg38)
End
61365293/62733817 (Hg38)
Orient
+
Location type
Intronic
Target gene
NTSR1
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-26b-5p
;
hsa-mir-1185-5p
;
hsa-mir-1249-5p
;
hsa-mir-1262
;
hsa-mir-1273h-5p
;
hsa-mir-1285-3p
;
hsa-mir-1321
;
hsa-mir-149-3p
;
hsa-mir-2392
;
hsa-mir-30b-3p
;
hsa-mir-3187-5p
;
hsa-mir-3605-5p
;
hsa-mir-3679-5p
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-378g
;
hsa-mir-4419a
;
hsa-mir-4486
;
hsa-mir-4505
;
hsa-mir-4510
;
hsa-mir-4701-3p
;
hsa-mir-4710
;
hsa-mir-4728-5p
;
hsa-mir-4731-5p
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-4779
;
hsa-mir-485-5p
;
hsa-mir-5189-5p
;
hsa-mir-5787
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-612
;
hsa-mir-6130
;
hsa-mir-6133
;
hsa-mir-615-5p
;
hsa-mir-661
;
hsa-mir-6735-3p
;
hsa-mir-6736-5p
;
hsa-mir-6742-3p
;
hsa-mir-6776-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6797-5p
;
hsa-mir-6799-5p
;
hsa-mir-6825-5p
;
hsa-mir-6860
;
hsa-mir-6871-5p
;
hsa-mir-6878-3p
;
hsa-mir-6883-5p
;
hsa-mir-6884-5p
;
hsa-mir-7106-5p
;
hsa-mir-7155-5p
;
hsa-mir-765
;
hsa-mir-7704
Nearest miRNA
hsa-mir-1-1/Upstream/168804; hsa-mir-124-3/Downstream/444683;
Nearest TSS
ENST00000382410/Upstream/24980;
ENST00000482259/Downstream/1530;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/23949
,
chr20-CpG: 22/Downstream/38138
Upstream sequence
aaagagagggagagaaggagagagagacacagagagaaagggaggaacagaggagagagaggggaggagggggagggagaCAGCACCCTCTTCTCCCTAC
Downstream sequence
CAGGCAGGGTCGCATTTTAAATGATGGTTTTGGGTGCTGAGCCAGCCCAGCTTGGAGGGGGTTTcgtttcacagatgaggagcctgaggctgggggaagc
Target sequence
CCTTGCCTGGGGTCTCAGCTGAGAGAGGGAAGGCTCTGTGCTGGGGAAGAGGCCTCCAGCAGGGAGTAGTGACTGATGAATGTATGATTGCTACTTTATCTCAATAGAGGATTCGAACAGCCCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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