Basic Information
VIS ID
TVIS30015948
Fusion event
HIV-chr21 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
14640068/13267747 (Hg38)
End
14640048/13267747 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10396a/Upstream/4280082; hsa-let-7c/Downstream/138637;
Nearest TSS
ENST00000624081/Upstream/251055; ENST00000624445/Downstream/37405;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/2640023, chr21-CpG: 39/Downstream/341868
Upstream sequence
cctcgtctctactaaaaatacaaaaaattagccgggcatagtggcgggcgcctgtagtcccagctactcgggaggctgggtcaggagaattgcgtgaacc
Downstream sequence
ctggaggcggagcttgcagtgagccgagattgcgccactgcactccagcctgggcgacacagtgagactccatctcaaataaataaataaataaataaat
Target sequence
tcaggagaattgcgtgaacc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate