Basic Information
VIS ID
TVIS30015951
Fusion event
HIV-C21orf91 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
19175189/17802872 (Hg38)
End
19175126/17802872 (Hg38)
Orient
-
Location type
Intronic
Target gene
C21orf91
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-100-5p ; hsa-mir-4662a-5p ; hsa-mir-4732-5p ; hsa-mir-6832-5p ; hsa-mir-4480 ; hsa-mir-6513-3p ; hsa-mir-3123 ; hsa-mir-3925-5p ; hsa-mir-1183 ; hsa-mir-595 ; hsa-mir-1911-5p ; hsa-mir-3065-3p ; hsa-mir-624-5p ; hsa-mir-634 ; hsa-mir-561-3p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-4698 ; hsa-mir-8485 ; hsa-mir-4694-3p ; hsa-mir-377-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-224-5p ; hsa-mir-2682-3p ; hsa-mir-3152-5p ; hsa-mir-374c-5p ; hsa-mir-4263 ; hsa-mir-429 ; hsa-mir-4724-5p ; hsa-mir-4799-5p ; hsa-mir-4999-3p ; hsa-mir-576-5p ; hsa-mir-655-3p ; hsa-mir-6781-3p ; hsa-mir-6836-3p ; hsa-mir-7850-5p ; hsa-mir-8084
Nearest miRNA
hsa-let-7c/Upstream/1212547; hsa-mir-155/Downstream/883218;
Nearest TSS
ENST00000624081/Upstream/9384; ENST00000454737/Downstream/6073;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/189493, chr21-CpG: 118/Downstream/15906
Upstream sequence
TGATGCTGAATGCCTTTATACTTCACACATTCTTGAATCATGTCATCTGACTCCCTCACACTTTTTGTGGTCAATTAGACTATATGTTGAATTGGATTAC
Downstream sequence
ATATTCCATTTCCCAACCAAAGGACTGGCTTTACATAACTTGGTGCTCCACAGGGAGAGCAAATATAATACAACCATCAGTGGATGTGAAGTTGTAATAT
Target sequence
TCATGTCATCTGACTCCCTCACACTTTTTGTGGTCAATTAGACTATATGTTGAATTGGATTAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate