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TVIS30015953
Basic Information
VIS ID
TVIS30015953
Fusion event
HIV-IFNAR2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
34607527/33235222 (Hg38)
End
34607618/33235222 (Hg38)
Orient
+
Location type
Intronic
Target gene
IFNAR2
miRNAs that regulate target gene
hsa-mir-106b-5p
;
hsa-mir-484
;
hsa-mir-18a-5p
;
hsa-mir-218-5p
;
hsa-mir-18b-5p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-651-3p
;
hsa-mir-4735-3p
;
hsa-mir-3591-5p
;
hsa-mir-5589-3p
;
hsa-mir-6730-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-30a-5p
;
hsa-mir-93-5p
;
hsa-mir-30c-5p
;
hsa-mir-30d-5p
;
hsa-mir-30b-5p
;
hsa-mir-30e-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-516b-3p
;
hsa-mir-516a-3p
;
hsa-mir-636
;
hsa-mir-651-5p
;
hsa-mir-1258
;
hsa-mir-2115-5p
;
hsa-mir-3678-3p
;
hsa-mir-3714
;
hsa-mir-7162-5p
;
hsa-mir-1273h-3p
;
hsa-mir-142-3p
;
hsa-mir-4280
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-6510-3p
;
hsa-mir-1228-5p
;
hsa-mir-6888-3p
;
hsa-mir-6729-5p
;
hsa-mir-4649-5p
;
hsa-mir-1273a
;
hsa-mir-4522
;
hsa-mir-6774-5p
;
hsa-mir-635
;
hsa-mir-3120-5p
;
hsa-mir-4538
;
hsa-mir-4453
;
hsa-mir-3664-5p
;
hsa-mir-506-3p
;
hsa-mir-124-3p
;
hsa-mir-2467-3p
;
hsa-mir-4771
;
hsa-mir-3166
;
hsa-mir-1265
;
hsa-mir-2392
;
hsa-mir-3910
;
hsa-mir-655-5p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-7150
;
hsa-mir-4737
;
hsa-mir-7977
;
hsa-mir-566
;
hsa-mir-4736
;
hsa-mir-4763-3p
;
hsa-mir-1207-5p
;
hsa-mir-6720-3p
;
hsa-mir-381-5p
;
hsa-mir-5690
;
hsa-mir-665
;
hsa-mir-4722-5p
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-1827
;
hsa-mir-4649-3p
;
hsa-mir-4756-5p
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-34b-3p
;
hsa-mir-629-3p
;
hsa-mir-4279
;
hsa-mir-7111-3p
;
hsa-mir-513a-5p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-342-3p
;
hsa-mir-4254
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
Nearest miRNA
hsa-let-7c/Upstream/2859844; hsa-mir-3197/Downstream/315440;
Nearest TSS
ENST00000624081/Upstream/4813;
ENST00000417007/Downstream/11552;
Nearest CpG islands
None/Target,
chr21-CpG: 261/Upstream/4262
,
chr21-CpG: 49/Downstream/30988
Upstream sequence
tagcatatgataagcagtgaggacagttttgtcaccatcttggttttggcaggctttggccagcttctttactgcgtcctgtcttatcagcagggtcttt
Downstream sequence
tcaagatggagtcactctggttccaacacctctgacaAGAGCAGGGGGTGACCTGTCACCTGGGGCTCAGCAGGACAATAACTCTAGGAAAAACTGGAAA
Target sequence
gtgacctcctgttttatcacataactaagaatgcctaaccccctgggaatgcagcccagcaggtctcagcctcattttacccagctgctac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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