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TVIS30015954
Basic Information
VIS ID
TVIS30015954
Fusion event
HIV-SON integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
34918474/33546168 (Hg38)
End
34918715/33546168 (Hg38)
Orient
+
Location type
Intronic
Target gene
SON
miRNAs that regulate target gene
hsa-mir-374b-5p
;
hsa-mir-130b-3p
;
hsa-mir-103a-3p
;
hsa-mir-30a-5p
;
hsa-mir-19b-3p
;
hsa-mir-18a-5p
;
hsa-mir-16-5p
;
hsa-mir-1301-3p
;
hsa-mir-760
;
hsa-mir-455-3p
;
hsa-mir-324-3p
;
hsa-mir-361-5p
;
hsa-mir-222-3p
;
hsa-mir-34a-5p
;
hsa-mir-17-5p
;
hsa-let-7b-5p
;
hsa-mir-126-5p
;
hsa-mir-412-3p
;
hsa-mir-8070
;
hsa-mir-3678-3p
;
hsa-mir-2467-3p
;
hsa-mir-4766-5p
;
hsa-mir-4289
;
hsa-mir-4282
;
hsa-mir-584-5p
;
hsa-mir-758-5p
;
hsa-mir-218-2-3p
;
hsa-mir-7849-3p
;
hsa-mir-4666a-3p
;
hsa-mir-6732-3p
;
hsa-mir-548as-3p
;
hsa-mir-10b-5p
;
hsa-mir-10a-5p
;
hsa-mir-6859-5p
;
hsa-mir-3916
;
hsa-mir-3125
;
hsa-mir-583
;
hsa-mir-1276
;
hsa-mir-4311
;
hsa-mir-4795-3p
;
hsa-mir-340-5p
;
hsa-mir-3163
;
hsa-mir-580-5p
;
hsa-mir-548ay-3p
;
hsa-mir-548at-3p
;
hsa-mir-548ap-3p
;
hsa-mir-548t-3p
;
hsa-mir-548aa
;
hsa-mir-203a-3p
;
hsa-mir-510-3p
;
hsa-mir-1303
;
hsa-mir-3140-3p
;
hsa-mir-208b-5p
;
hsa-mir-208a-5p
;
hsa-mir-100-3p
;
hsa-mir-561-3p
;
hsa-mir-548at-5p
;
hsa-mir-142-5p
;
hsa-mir-5590-3p
;
hsa-mir-3529-3p
;
hsa-mir-135b-3p
;
hsa-mir-4278
;
hsa-mir-6887-5p
;
hsa-mir-6795-5p
;
hsa-mir-4652-5p
;
hsa-mir-8052
;
hsa-mir-3199
;
hsa-mir-6732-5p
;
hsa-mir-6805-5p
;
hsa-mir-6794-5p
;
hsa-mir-4716-3p
;
hsa-mir-574-5p
;
hsa-mir-6867-5p
;
hsa-mir-1273d
;
hsa-mir-1295b-5p
;
hsa-mir-1912
;
hsa-mir-21-3p
;
hsa-mir-3180-5p
;
hsa-mir-3591-3p
;
hsa-mir-375
;
hsa-mir-3919
;
hsa-mir-520a-5p
;
hsa-mir-525-5p
;
hsa-mir-6739-3p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-1225-5p
;
hsa-mir-1229-5p
;
hsa-mir-153-5p
;
hsa-mir-186-5p
;
hsa-mir-20a-5p
;
hsa-mir-20b-5p
;
hsa-mir-302a-3p
;
hsa-mir-302b-3p
;
hsa-mir-302c-3p
;
hsa-mir-302d-3p
;
hsa-mir-302e
;
hsa-mir-3133
;
hsa-mir-372-3p
;
hsa-mir-373-3p
;
hsa-mir-4422
;
hsa-mir-4720-3p
;
hsa-mir-4804-3p
;
hsa-mir-519d-3p
;
hsa-mir-520a-3p
;
hsa-mir-520b
;
hsa-mir-520c-3p
;
hsa-mir-520d-3p
;
hsa-mir-520e
;
hsa-mir-520f-3p
;
hsa-mir-526b-3p
;
hsa-mir-548az-5p
;
hsa-mir-548c-3p
;
hsa-mir-548e-5p
;
hsa-mir-548n
;
hsa-mir-548t-5p
;
hsa-mir-551b-5p
;
hsa-mir-555
;
hsa-mir-5692a
;
hsa-mir-633
;
hsa-mir-93-5p
Nearest miRNA
hsa-let-7c/Upstream/3170790; hsa-mir-3197/Downstream/4494;
Nearest TSS
ENST00000624081/Upstream/2677;
ENST00000421541/Downstream/6080;
Nearest CpG islands
None/Target,
chr21-CpG: 261/Upstream/2792
,
chr21-CpG: 86/Downstream/41914
Upstream sequence
GCATTATTAGTGGTGAATATCTAAAATAGGAAAAAGGTAAAACATCTGACAGTCAGTACAACATATGATTATTGTAATTAATTGGATTTTTTTATTAATG
Downstream sequence
ATTTTCTTTTAAGATTTTTTTGAAATTTGAAGGTTAATGTTAGTTTTTGACTTCAGTATTTAAGATATTTATTAAATTAAAAACTTTAggctgggtgcga
Target sequence
GTATGATAAAATATTAATGAATTTCGATAACTTTTCATGTCAAGTGGAAGGAATGAAGGCCAGCTGAATGGTGAAACAAATACACCCATTGAAGGAAACCAGGCGGGTGATGCAGCTGCCTCTGCCAGGAGTCTACCAAATGAAGAAATAGTGCAGAAGATAGAGGAAGTACTTTCTGGGGTCTTAGATACAGAACTACGATATAAGCCAGGTAAGTTGGAGATAATTAACTGTCTCAAAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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