Basic Information
VIS ID
TVIS30015965
Fusion event
HIV-chr21 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
46342467/44922552 (Hg38)
End
46342548/44922552 (Hg38)
Orient
+
Location type
Intronic
Nearest miRNA
hsa-let-7c/Upstream/1312563; hsa-mir-6815/Downstream/555714;
Nearest TSS
ENST00000624081/Upstream/1226; ENST00000609953/Downstream/6166;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/18515, chr21-CpG: 134/Downstream/8861
Upstream sequence
aggagttcgagaccagcctaggcaacatttggagacccagaccctcatctctacaaaaaaattttctaagaattcgccaggcatggtagcacgcgatatg
Downstream sequence
ctgcactccagtctgggtaactgagaaaaaaaaaaaaaaaaaaaggcaaatcctttaaaagaaaaaagtaagggaaaatagaacaaacaagaaaggtaaa
Target sequence
gtccaggctacttgggaggctgaggtgggagaattgcttgagcccaagaggttgaggctacggtgaaccatgcttacacca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate