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TVIS30015978
Basic Information
VIS ID
TVIS30015978
Fusion event
HIV-DIP2A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
47990527/46570614 (Hg38)
End
47990359/46570614 (Hg38)
Orient
-
Location type
Intronic
Target gene
DIP2A
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-423-5p
;
hsa-mir-484
;
hsa-mir-125a-5p
;
hsa-mir-142-3p
;
hsa-mir-548c-3p
;
hsa-mir-4435
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-3194-5p
;
hsa-mir-1204
;
hsa-mir-132-5p
;
hsa-mir-6504-3p
;
hsa-mir-3934-5p
;
hsa-mir-6858-3p
;
hsa-mir-552-3p
;
hsa-mir-6818-3p
;
hsa-mir-593-3p
;
hsa-mir-6895-3p
;
hsa-mir-4496
;
hsa-mir-6124
;
hsa-mir-6859-5p
;
hsa-mir-3916
;
hsa-mir-3125
;
hsa-mir-583
;
hsa-mir-7641
;
hsa-mir-6778-3p
;
hsa-mir-4695-3p
;
hsa-mir-2276-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-1281
;
hsa-mir-4485-5p
;
hsa-mir-6791-5p
;
hsa-mir-4292
;
hsa-mir-4308
;
hsa-mir-548aw
;
hsa-mir-513b-5p
;
hsa-mir-1185-2-3p
;
hsa-mir-1185-1-3p
;
hsa-let-7f-2-3p
;
hsa-mir-4789-5p
;
hsa-mir-98-3p
;
hsa-let-7f-1-3p
;
hsa-let-7b-3p
;
hsa-let-7a-3p
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-125b-2-3p
;
hsa-mir-4457
;
hsa-mir-8063
;
hsa-mir-1179
;
hsa-mir-551b-5p
;
hsa-mir-3161
;
hsa-mir-891b
;
hsa-mir-550b-3p
;
hsa-mir-3664-5p
;
hsa-mir-514a-5p
;
hsa-mir-4714-5p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-3157-5p
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-676-5p
;
hsa-mir-4691-3p
;
hsa-mir-5697
;
hsa-mir-6741-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-6873-3p
;
hsa-mir-6867-3p
;
hsa-mir-630
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6845-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4469
Nearest miRNA
hsa-let-7c/Upstream/1092288;
Nearest TSS
ENST00000624081/Upstream/6954;
ENST00000491389/Downstream/32279;
Nearest CpG islands
None/Target,
chr21-CpG: 261/Upstream/71799
,
chr21-CpG: 21/Downstream/28015
Nearby gene
DIP2A
(No orient, 14095)
Upstream sequence
CATATACTTCTTACTTTTTCTTGTGGGTTATTTGTATTTTGGTTCTATCTGTTTTGGTGCAGATGGTTTTTTAGATGTTATATTTATGCAAACTGGTTAT
Downstream sequence
TGTGTTTGATTTCAGATTATGAATATAGCTGATTTATTTCAAAGTGGTTCTACTGGAATGATCAGCATAAACCAATGGGGAGTACATGGCAGAGAAATAA
Target sequence
cagtccttatggtcaagttttttcttactgacatgtaggagtctctttctattaagaatTATAACCTCCATATACTTCTTACTTTTTCTTGTGGGTTATTTGTATTTTGGTTCTATCTGTTTTGGTGCAGATGGTTTTTTAGATGTTATATTTATGCAAACTGGTTAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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