Basic Information
VIS ID
TVIS30016036
Fusion event
HIV-HORMAD2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
End
30515269/30119419 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1286/Upstream/112306; hsa-let-7a-3/Downstream/612138;
Upstream sequence
GCTCTGTCTAGCCATTAATTCAAAGTTTCTCAACTGCtatgcctagatagcgatcctttccacctcgatatagccagcctgtgcctagggtagataatac
Downstream sequence
ccttggactatttgcccgtatgcacaaatattctcatttgcttaccccagtatgtcatataaatatcatttccttgtgtccttgtatgaaaagattagaa
Target sequence
AAGGTTGCCTACACGCTATTGATTGAATAACTCCATAAGGCTCTGTCTAGCCATTAATTCAAAGTTTCTCAACTGCtatgcctagatagcgatcctttccacctcgatatagccagcctgtgcctagggtagataatac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate