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TVIS30016065
Basic Information
VIS ID
TVIS30016065
Fusion event
HIV-PRR14L integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
32096142/31700156 (Hg38)
End
32096244/31700156 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22B
Target gene
PRR14L
miRNAs that regulate target gene
hsa-mir-27a-3p
;
hsa-mir-1914-5p
;
hsa-mir-1254
;
hsa-mir-505-5p
;
hsa-mir-671-5p
;
hsa-mir-615-3p
;
hsa-mir-484
;
hsa-mir-320a
;
hsa-mir-23b-3p
;
hsa-mir-92a-3p
;
hsa-mir-5011-5p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-4470
;
hsa-mir-4268
;
hsa-mir-3155b
;
hsa-mir-3155a
;
hsa-mir-3714
;
hsa-mir-3910
;
hsa-mir-124-3p
;
hsa-mir-506-3p
;
hsa-mir-302c-5p
;
hsa-mir-3138
;
hsa-mir-302d-5p
;
hsa-mir-302b-5p
;
hsa-mir-545-5p
;
hsa-mir-4686
;
hsa-mir-3974
;
hsa-mir-4796-3p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-500a-3p
;
hsa-mir-203a-3p
;
hsa-mir-6804-3p
;
hsa-mir-633
;
hsa-mir-4703-5p
;
hsa-mir-4643
;
hsa-mir-3942-5p
;
hsa-mir-107
;
hsa-mir-103a-3p
;
hsa-mir-203b-3p
;
hsa-mir-7158-3p
;
hsa-mir-591
;
hsa-mir-410-3p
;
hsa-mir-5692b
;
hsa-mir-5692c
;
hsa-mir-888-3p
;
hsa-mir-1277-5p
;
hsa-mir-606
;
hsa-mir-3124-5p
;
hsa-mir-8052
;
hsa-mir-3199
;
hsa-mir-3607-3p
;
hsa-mir-130b-5p
;
hsa-mir-3140-5p
;
hsa-mir-4668-3p
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-93-5p
;
hsa-mir-17-5p
;
hsa-mir-1183
;
hsa-mir-1284
;
hsa-mir-1-3p
;
hsa-mir-182-3p
;
hsa-mir-19a-5p
;
hsa-mir-19b-1-5p
;
hsa-mir-19b-2-5p
;
hsa-mir-2052
;
hsa-mir-2053
;
hsa-mir-206
;
hsa-mir-214-3p
;
hsa-mir-21-5p
;
hsa-mir-3125
;
hsa-mir-3137
;
hsa-mir-3619-5p
;
hsa-mir-377-5p
;
hsa-mir-3916
;
hsa-mir-4291
;
hsa-mir-4469
;
hsa-mir-4684-5p
;
hsa-mir-4751
;
hsa-mir-510-5p
;
hsa-mir-512-5p
;
hsa-mir-520f-5p
;
hsa-mir-548n
;
hsa-mir-5571-5p
;
hsa-mir-5579-3p
;
hsa-mir-5690
;
hsa-mir-569
;
hsa-mir-590-5p
;
hsa-mir-6086
;
hsa-mir-613
;
hsa-mir-655-5p
;
hsa-mir-6787-3p
;
hsa-mir-6859-5p
;
hsa-mir-761
;
hsa-mir-8055
;
hsa-mir-877-5p
;
hsa-mir-922
Nearest miRNA
hsa-mir-1286/Upstream/78625; hsa-let-7a-3/Downstream/1736426;
Nearest TSS
ENST00000624155/Upstream/37724;
ENST00000469969/Downstream/3562;
Nearest CpG islands
None/Target,
chr22-CpG: 279/Upstream/37819
,
chr22-CpG: 58/Downstream/49493
Upstream sequence
cgccagacactgagacagtaactgccactaatgcctgggcaacagaacctttgtgactgagtgcttttcaatcttttgttttccttaaatataatgctag
Downstream sequence
aacaaggttcttcagacatataaatgcaagagagaatagaactgataatgaatcctatttcattcgagtaataaatactacccgatctcggatatctgaa
Target sequence
atcactctatgattttttggcatataacttgaaagaagtggaaataattgaatgactttactatattaaaactctttcctctcccaactacttatttatgta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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