VISDB Viral Integration Site DataBase

VIS ID

TVIS30016070

Fusion event

HIV-APOBEC3C integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr22

Cytoband

q13.1

Reference genome

Start

End

39482394/39086724 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-92a-3p ; hsa-mir-1910-3p ; hsa-mir-1911-3p ; hsa-mir-24-3p ; hsa-mir-3184-5p ; hsa-mir-3621 ; hsa-mir-3664-3p ; hsa-mir-3934-3p ; hsa-mir-423-5p ; hsa-mir-4283 ; hsa-mir-4437 ; hsa-mir-4459 ; hsa-mir-4514 ; hsa-mir-4645-5p ; hsa-mir-4673 ; hsa-mir-4692 ; hsa-mir-4779 ; hsa-mir-5008-5p ; hsa-mir-6085 ; hsa-mir-6089 ; hsa-mir-6511a-5p ; hsa-mir-665 ; hsa-mir-6744-5p ; hsa-mir-6813-5p ; hsa-mir-1273f ; hsa-mir-129-5p ; hsa-mir-185-3p ; hsa-mir-3674 ; hsa-mir-3675-5p ; hsa-mir-4489 ; hsa-mir-4732-5p ; hsa-mir-6832-5p

Nearest miRNA

hsa-mir-1286/Upstream/1097871; hsa-let-7a-3/Downstream/1727159;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/159201, chr22-CpG: 107/Downstream/58293

Upstream sequence

AAGTTACTAGAAAGTGGGGAGGGTCGGCATCCCTGTGGGAAAGGCCTTGATCCTCTGCCTGCAGAGGCGATGGCTGCACTCTGGACCTGACTTTGGGGTC

Downstream sequence

GACGGGAAGAGAGAGGCCAGGCCAGGAGATGTGGACCTGGGGAGGGCGGGGAGGGTGGCTGGAAGTGGAAGCAGAACTTGGGGCTTCCAGAAAAAATGAG

Target sequence

ACCTCCTGGAGCCCCTGCTTCAGCTGTGCCCAGGAAATGGCTAAATTCATTTCAAAAAACAAACACGTGAGCCTGTGCATCTTCACTGCCCGCATCTATGATGATCAAGGAAGATGTCAGGAGGGGCTGCGCACCCTGGCCGAGGCTGGGGCCAAAATTTCAATAATGACATACAGTGGTGAGAATGGAAGCCTGGAGTAGGATGGGGTCAGCCAGGGCAGGAGAGGGCCCCGGGAAGTTACTAGAAAGTGGGGA