Basic Information
VIS ID
TVIS30016094
Fusion event
HIV-PACSIN2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
End
43372689/42977015 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1281/Upstream/1053718; hsa-let-7a-3/Downstream/2223939;
Nearby gene
PACSIN2(No orient, 17134)
Upstream sequence
CTAGAAGTTTCTCCAGCCGACACAATACCTCatgttatgctatccttgcattgctagagtaaaccttgtttggtcatgaaaaattaatcttttaatacac
Downstream sequence
tactgtattcaaattattatttgatttagaaACCTACTTTAAAATGTTGCAAATATATAAACATATATATGCATTAATAGACACATATTACATTCATATG
Target sequence
GTGAATTGTGATGTATaacattaactgagcacttattatgcaccaaacccaggtctaatcatttcacagataccccatttcgtccttccatcaaccctatacagcagtattgtaattgtcctgccaattttatagatgaggagactgaagctcagggagattaactaatttggctaacgtcagagaattagtaaatggcaggactggggcaaaccatgctctaatccctgagCTAGAAGTTTCTCCAGCCGACAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate