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TVIS30016114
Basic Information
VIS ID
TVIS30016114
Fusion event
HIV-EDEM1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p26.1
Reference genome
GRCh37/hg19
Start
5240691/5199006 (Hg38)
End
5240495/5199006 (Hg38)
Orient
-
Location type
Intronic
Target gene
EDEM1
miRNAs that regulate target gene
hsa-mir-204-5p
;
hsa-mir-335-5p
;
hsa-mir-32-5p
;
hsa-mir-125b-5p
;
hsa-mir-100-5p
;
hsa-mir-96-5p
;
hsa-mir-581
;
hsa-mir-25-3p
;
hsa-mir-92a-3p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-92b-3p
;
hsa-mir-4330
;
hsa-mir-4793-3p
;
hsa-mir-6715a-3p
;
hsa-mir-19a-5p
;
hsa-mir-19b-1-5p
;
hsa-mir-19b-2-5p
;
hsa-mir-491-3p
;
hsa-mir-1468-3p
;
hsa-mir-1301-3p
;
hsa-mir-548f-5p
;
hsa-mir-548g-5p
;
hsa-mir-548x-5p
;
hsa-mir-548aj-5p
;
hsa-mir-4660
;
hsa-mir-5047
;
hsa-mir-548aw
;
hsa-mir-10b-3p
;
hsa-mir-3922-5p
;
hsa-mir-6885-3p
;
hsa-mir-2052
;
hsa-mir-5692a
;
hsa-mir-548c-3p
;
hsa-mir-4261
;
hsa-mir-549a
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-3613-3p
;
hsa-mir-888-5p
Nearest miRNA
hsa-let-7g/Downstream/51171;
Nearest TSS
ENST00000440867/Upstream/3900;
ENST00000425894/Downstream/57755;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/10501
,
chr3-CpG: 71/Downstream/1662130
Upstream sequence
CCAACTGTGCTTCACATAGGAGAGAGTGGCTTAGTGTGACGTCGTATCTACATACCCAAAATAGGAATCATAATTCTAGATCACTTTTTAAAAAGGACAT
Downstream sequence
AGAGCTGATTATTCATATGTTTTGTTTCTTTTAAATCAGTCACTGGTTTTATCCTGTGCTCCAAAAGATATTACCACTATTTCTCAAAGTGTTTAGGCAT
Target sequence
TATGTCCTTATGATGTCATTATAGTCTCAGGGTTGTCATAAAATTTAGAGTGGAATGAAATAATTTTGATTCAGGTTAATCTATAAAGTTTGATGCCCAACTGTGCTTCACATAGGAGAGAGTGGCTTAGTGTGACGTCGTATCTACATACCCAAAATAGGAATCATAATTCTAGATCACTTTTTAAAAAGGACAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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