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TVIS30016116
Basic Information
VIS ID
TVIS30016116
Fusion event
HIV-NR2C2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
15036603/14995096 (Hg38)
End
15036569/14995096 (Hg38)
Orient
-
Location type
Intronic
Target gene
NR2C2
miRNAs that regulate target gene
hsa-mir-21-5p
;
hsa-mir-615-3p
;
hsa-mir-26b-5p
;
hsa-mir-143-3p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-599
;
hsa-mir-3161
;
hsa-mir-4795-3p
;
hsa-mir-556-3p
;
hsa-mir-7848-3p
;
hsa-mir-466
;
hsa-mir-4672
;
hsa-mir-3941
;
hsa-mir-4490
;
hsa-mir-126-5p
;
hsa-mir-656-3p
;
hsa-mir-4643
;
hsa-mir-4789-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-302c-3p
;
hsa-mir-520f-3p
;
hsa-mir-106a-5p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-17-5p
;
hsa-mir-526b-3p
;
hsa-mir-93-5p
;
hsa-mir-520b
;
hsa-mir-520c-3p
;
hsa-mir-520d-3p
;
hsa-mir-520a-3p
;
hsa-mir-520e
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302a-3p
;
hsa-mir-302b-3p
;
hsa-mir-10a-5p
;
hsa-mir-10b-5p
;
hsa-mir-504-5p
;
hsa-mir-587
;
hsa-mir-374b-5p
;
hsa-mir-6884-3p
;
hsa-mir-374a-5p
;
hsa-mir-501-5p
;
hsa-mir-500a-5p
;
hsa-mir-605-5p
;
hsa-mir-6083
;
hsa-mir-190a-3p
;
hsa-mir-4789-5p
;
hsa-mir-5011-5p
;
hsa-mir-8083
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-1277-5p
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-133a-3p
;
hsa-mir-10a-3p
;
hsa-mir-203a-3p
Nearest miRNA
hsa-mir-12127/Upstream/4600534; hsa-let-7g/Downstream/501143;
Nearest TSS
ENST00000440867/Upstream/32687;
ENST00000495282/Downstream/8819;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/46619
,
chr3-CpG: 70/Downstream/69689
Nearest cancer related gene
NR2C2
(TSG, No orient, 0)
Upstream sequence
ttgagataagttctcattctgtcacccaggctggagtgaatttgcacaatcatagctcactgcagccttgaccctccggtcgagttgaaccctctgggtt
Downstream sequence
caagtgagtctcccacctcagcctcctaagcagctgagaccacagacacacgccatcacgcctggctagtttttttaattttttaatagagaccaagttt
Target sequence
cttgaccctccggtcgagttgaaccctctgggtt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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