Basic Information
VIS ID
TVIS30016117
Fusion event
HIV-NR2C2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
End
15036580/14995096 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12127/Upstream/4600534; hsa-let-7g/Downstream/501143;
Nearest cancer related gene
NR2C2(TSG, No orient, 0)
Upstream sequence
ttgagataagttctcattctgtcacccaggctggagtgaatttgcacaatcatagctcactgcagccttgaccctccggtcgagttgaaccctctgggtt
Downstream sequence
caagtgagtctcccacctcagcctcctaagcagctgagaccacagacacacgccatcacgcctggctagtttttttaattttttaatagagaccaagttt
Target sequence
ggtcgagttgaaccctctgggtt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate