Basic Information
VIS ID
TVIS30016118
Fusion event
HIV-chr3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
15294446/15252939 (Hg38)
End
15294534/15252939 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/4858377; hsa-let-7g/Downstream/243300;
Nearest TSS
ENST00000440867/Upstream/5702; ENST00000413977/Downstream/1245;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/46126, chr3-CpG: 100/Downstream/78868
Nearby gene
CAPN7(No orient, 23)
Upstream sequence
ttgagtgtttactatgtacccaatgtgtatatttttctttttaatcttcccaatagctgaataaagtatagatactattatttgtacttcttacaattga
Downstream sequence
TGGCACCCACAGTCACGGCCGTCTAGTCGAGGGAGGGACAAGATCTAGACCCATTGTAGAGGGAGGAAAAACAATCCAGGCCTTTTGGAGGTTCTAAATA
Target sequence
ggaaataagcctaagagattaaaagattttgcccagggttcacaAGCCTTCTTCCCTGAGCCCTGATTGAGCTGCTGTGTGTGTCTAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate