Basic Information
VIS ID
TVIS30016119
Fusion event
HIV-ANKRD28 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
15719842/15678335 (Hg38)
End
15719871/15678335 (Hg38)
Orient
+
Location type
Exonic
Target gene
ANKRD28
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-21-5p ; hsa-mir-221-3p ; hsa-mir-130b-5p ; hsa-mir-3180-5p ; hsa-mir-513b-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6885-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-942-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3617-3p ; hsa-mir-3074-3p ; hsa-mir-3614-3p
Nearest miRNA
hsa-mir-12127/Upstream/182027; hsa-let-7g/Downstream/18963;
Nearest TSS
ENST00000440867/Upstream/729; ENST00000470031/Downstream/8118;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/76261, chr3-CpG: 142/Downstream/180655
Upstream sequence
CAGCCATCATAAGAGGTGTTTTCCCTGTAGAGTCCACAGAATTGACTTGAGCATTATGGCTGAGCAGCAGCTGTAAACACTCTACATGGTCTGTGAAGGC
Downstream sequence
GAAAAATTGAAATATATGACTAAATTTGAATGTTATATATGCTGGAAAAATATTCTTTAATTTGTGACATGCTGTTTTTAAGGGTTTACATATTAGGCTA
Target sequence
GGCTGCATGGAGAGGAGTTCTGTGATAAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate