Basic Information
VIS ID
TVIS30016120
Fusion event
HIV-RFTN1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
16424668/16383161 (Hg38)
End
16424609/16383161 (Hg38)
Orient
-
Location type
Intronic
Target gene
RFTN1
miRNAs that regulate target gene
hsa-mir-484
Nearest miRNA
hsa-mir-12127/Upstream/509312; hsa-let-7g/Downstream/550035;
Nearest TSS
ENST00000440867/Upstream/12195; ENST00000596963/Downstream/51609;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/117682, chr3-CpG: 113/Downstream/129659
Upstream sequence
AATCATACCttacagaagagaaaactgcttaagacattctgtgactggtcaaacctcacagaactacccaaagccatgcctggctttcgctctgagtatc
Downstream sequence
ctaagcccaacctgatgcctcttcaacgataccactctttccACTTCAGATAATCTGACCTGTGCCAAGATGCCCAGGTGGATGCCTGTTTAAACTGATA
Target sequence
tgactggtcaaacctcacagaactacccaaagccatgcctggctttcgctctgagtatc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate