Basic Information
VIS ID
TVIS30016126
Fusion event
HIV-chr3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
46386611/46345120 (Hg38)
End
46386494/46345120 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/1483139; hsa-let-7g/Downstream/1504435;
Nearest TSS
ENST00000440867/Upstream/79992; ENST00000421659/Downstream/8614;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/349139, chr3-CpG: 26/Downstream/119551
Nearby gene
CCR2(No orient, 8623)
Upstream sequence
ATGCAgcagccattaaaattatgtttatgaataatttacagcatggaaaaatttggggttgctagtagaaaaacaaaaaggtacaaaaggatatatataa
Downstream sequence
taagcctacaatgccatataaacaatactaacagcaaaaacaaacctataaattgggggaagatggggcagatagaagtaacctaaaatactaacatgtt
Target sequence
TGAACCATTTGACCAGTATGCAgcagccattaaaattatgtttatgaataatttacagcatggaaaaatttggggttgctagtagaaaaacaaaaaggtacaaaaggatatatataa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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