VISDB Viral Integration Site DataBase

VIS ID

TVIS30016128

Fusion event

HIV-SETD2 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr3

Cytoband

p21.31

Reference genome

Start

End

47095998/47054302 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-106b-5p ; hsa-mir-26a-5p ; hsa-mir-199b-5p ; hsa-mir-21-5p ; hsa-mir-186-5p ; hsa-mir-526b-3p ; hsa-mir-199a-5p ; hsa-mir-1289 ; hsa-mir-3198 ; hsa-mir-3658 ; hsa-mir-3667-5p ; hsa-mir-4294 ; hsa-mir-4309 ; hsa-mir-4726-3p ; hsa-mir-5702

Nearest miRNA

hsa-mir-12127/Upstream/2192321; hsa-let-7g/Downstream/795253;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/44183, chr3-CpG: 172/Downstream/108997

Nearest cancer related gene

SETD2(TSG, No orient, 0)

Upstream sequence

TCTTGATAGGGACAGAATGAAAGACTAGAAGCAAGTAAATTGTGATGCTTGGCTCTTAGGGCTAATGAATAAAACCAAGAGAATCTTTTTTTCTCATTGG

Downstream sequence

TGGCTTGGTCCAAGAAAGAATATGGCTCATACCCAAGTCAAACTGACAGTAAAACAAAACCAAAACCAAAACCCAAAACATTCTGTAGGAGGGAGAATGA

Target sequence

GAAGGAATAAATGGATTTTATTTTATAAGAAAAATCATATGACCAGGGAGCTCTTTACTGAGGAGTCTTTAATGGATATCTTTCATTGCTGTTGCTTAGGCTCTAGTACTGAGATGGGACCTATTTCAGGAATAGGAATGGGGATAGACATAAACCATTTTTACTGTATCCCTGATACATATTTTTAGGGAAAAACTCAAAACTAA