Basic Information
VIS ID
TVIS30016144
Fusion event
HIV-USP4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
49375155/49337722 (Hg38)
End
49375200/49337722 (Hg38)
Orient
+
Location type
Intronic
Target gene
USP4
miRNAs that regulate target gene
hsa-mir-148a-3p
Nearest miRNA
hsa-mir-12127/Upstream/63536; hsa-let-7g/Downstream/468415;
Nearest TSS
ENST00000440867/Upstream/18948; ENST00000497786/Downstream/2307;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/60340, chr3-CpG: 42/Downstream/2185
Nearest cancer related gene
USP4(OG, No orient, 0)
Upstream sequence
ggctagctcttgctatgttgcccaggctggtcttgaactcctggcctcaagtgatcctcctgcctcagcttcccaaagtgctgggattacaggcatgagc
Downstream sequence
ccgggagcggtggctcacgcctgtaatcccagcactttgggaggctgagtcaggtggatcacgaggtcaggagatcgagaccatcctggccaacatggtg
Target sequence
cactgcaccagaccTGTTTATATTTTTAAAGTATCACTGTGCTgg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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