Basic Information
VIS ID
TVIS30016159
Fusion event
HIV-DCAF1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
51482755/51448739 (Hg38)
End
51482855/51448739 (Hg38)
Orient
+
Location type
Intronic
Target gene
DCAF1
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-12127/Upstream/773576; hsa-let-7g/Downstream/819539;
Nearest TSS
ENST00000440867/Upstream/57471; ENST00000602430/Downstream/35099;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/55433, chr3-CpG: 76/Downstream/50587
Upstream sequence
ataattcagtaggactaagtacattcaaaatgttaaataactattaccggtatagtatctattttcagaacttcttcattatgcaaacaaaaactctgta
Downstream sequence
acagaaaactccacccaacaacagtagattacacagtcttctcaagtacacatagaactttttccatgttcttttatgttttttttttcccagagtaaac
Target sequence
cccctcactttcaattacgattaagacaaccagacagaagatcaataaggaaacagagaacttgaacaacactataagccattgaacctaaaagatgtac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate