Basic Information
VIS ID
TVIS30016161
Fusion event
HIV-SFMBT1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
52952495/52918479 (Hg38)
End
52952466/52918479 (Hg38)
Orient
-
Location type
Intronic
Target gene
SFMBT1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-let-7g/Upstream/71927; hsa-mir-12124/Downstream/2934013;
Nearest TSS
ENST00000440867/Upstream/20883; ENST00000477794/Downstream/10016;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/20655, chr3-CpG: 22/Downstream/80318
Upstream sequence
AAAATTATGCTTCCATCTGAGAAAATGAGGAAATATACCCTCTGAAATAGTTATTTTTCTAGATATTCTAACTTGTAAACTGTTCATATTATTACGTTAC
Downstream sequence
TTACTGTTTTTCTGGCTGAACCACTGCAATTTTCCTCTGTTTATATACTGTAGAAAGAAAAAAATATATAAATGCCAAGAAAAATAAAAAGACAAAGGAA
Target sequence
CTTGTAAACTGTTCATATTATTACGTTAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate