Basic Information
VIS ID
TVIS30016163
Fusion event
HIV-SLMAP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
57830799/57845072 (Hg38)
End
57830539/57845072 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLMAP
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-21-5p ; hsa-mir-19b-3p
Nearest miRNA
hsa-let-7g/Upstream/1992478; hsa-mir-12124/Downstream/2772733;
Nearest TSS
ENST00000440867/Upstream/87514; ENST00000475055/Downstream/16928;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/87809, chr3-CpG: 90/Downstream/163039
Upstream sequence
TAAGTTCATTTCACTatatgtgcatatctgcagagaaaaggatatatacccacaatggttatctctgagtgctggtattgagtaatttttatgtatttcc
Downstream sequence
tcatgatttacttcacacattttccataatcaatatttgttaTATTCAAGAAAAATAAATTATTGTTTAAAATGCCTATTTCAATGTTCTGGAGTAAAGT
Target sequence
caagtgattctcctgcctcagcctcccaggtagctgggattacaggtgccctccactacacccggctggtttttgtatttttagtagaaacaggtttcaccatgttggccaggctgttcccaaactcctaacctcaaatcatctgGCATTTAGACATTCTTAAGTTCATTTCACTatatgtgcatatctgcagagaaaaggatatatacccacaatggttatctctgagtgctggtattgagtaatttttatgta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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