Basic Information
VIS ID
TVIS30016164
Fusion event
HIV-LOC105377110 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
59521453/59535727 (Hg38)
End
59521483/59535727 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
LOC105377110
Nearest miRNA
hsa-let-7g/Upstream/3683133; hsa-mir-12124/Downstream/1082078;
Nearest TSS
ENST00000440867/Upstream/25049; ENST00000475527/Downstream/478423;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/485509, chr3-CpG: 48/Downstream/1715205
Nearby gene
FHIT(No orient, 213582)
Upstream sequence
GAAGCTTTAGAAAAATTTAATCCTTTAGTGAAAAGGGGCTAACAATCGACAGTATGCTGTGGTCATGTTGATTTAATTATCAAACAGAACAAAATTGTTG
Downstream sequence
TATTAAGGGCAGTCTTGGCTGGGGATTGAGTCTTTAAAAGCTCGTTTGTTTTGTTTTGTTTGAAAATGTTTAACCCAAAAACTTGGATAACAGGCTGAAT
Target sequence
ATTACTTAATGATTAATAGTAACAAAGAGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate