Basic Information
VIS ID
TVIS30016166
Fusion event
HIV-TMF1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
69093696/69044545 (Hg38)
End
69093654/69044545 (Hg38)
Orient
-
Location type
Exonic
Target gene
TMF1
miRNAs that regulate target gene
hsa-mir-32-5p ; hsa-mir-1914-5p ; hsa-mir-484 ; hsa-mir-424-5p ; hsa-mir-331-3p ; hsa-mir-362-5p ; hsa-mir-92a-3p ; hsa-mir-4324 ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-32-3p ; hsa-mir-5692a ; hsa-mir-363-3p ; hsa-mir-92b-3p ; hsa-mir-25-3p ; hsa-mir-367-3p ; hsa-mir-3613-3p ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-3149 ; hsa-mir-5096 ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-197-3p ; hsa-mir-6832-5p ; hsa-mir-411-5p ; hsa-mir-193b-5p ; hsa-mir-4755-3p ; hsa-mir-1273f ; hsa-mir-6890-5p ; hsa-mir-4735-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p
Nearest miRNA
hsa-let-7g/Upstream/1819018; hsa-mir-12124/Downstream/4413;
Nearest TSS
ENST00000440867/Upstream/9449; ENST00000610844/Downstream/83;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/30506, chr3-CpG: 39/Downstream/7525
Upstream sequence
GTTTCCAGAAAATGTGTAACATTATTCACATTTGCAGAATACTTACTCTTTCAGGTTATCAAAAGCTTCTTCTAGAAGTGCTTTTTCCTTACTAAGAGAT
Downstream sequence
AATAACTGAGCCTCCCTTTTTTCCAGCTTTTCATTCAGAAATTCAACTGTCTGGATAAGGCGAATACATAAAAGTCAGAACGCTTAGCTTTAAAAAAGAC
Target sequence
TCAAAAGCTTCTTCTAGAAGTGCTTTTTCCTTACTAAGAGAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate