Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene141465180141487047141615342141484879141491307141538491141543162141497589141501618141531635141534463141506869141509394141528601141531060141513261141514843141494781141495865141492981141493507141525001141525400141504513141504909141540261
Basic Information
VIS ID
TVIS30016178
Fusion event
HIV-RASA2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q23
Reference genome
GRCh37/hg19
Start
141259103/141540261 (Hg38)
End
141258995/141540261 (Hg38)
Orient
-
Location type
Intronic
Target gene
RASA2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-182-5p ; hsa-mir-203a-3p ; hsa-mir-4470 ; hsa-mir-3973 ; hsa-mir-4635 ; hsa-mir-548l
Nearest miRNA
hsa-let-7g/Upstream/7102355; hsa-mir-1224/Downstream/10025615;
Nearest TSS
ENST00000440867/Upstream/53177; ENST00000505833/Downstream/38263;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/52343, chr3-CpG: 56/Downstream/119615
Upstream sequence
TGTCCTTAATGCTGGTTTATCTTCTGGAAAAAGCATCCTACATTTTATAATTTGGTTTTATCTCAAAATTTCCTTAAATTTAGGTATTGTCTTTCCTTTT
Downstream sequence
AGTCTGTGATAATTAGATATATAAATATTTATTGAATTGGACATAAAATTCTTAAATTTGAATACCATGTTTGACATAAGTATTTGTTTCATATCTTTCA
Target sequence
ACTGCTTCTGTCCTTAATGCTGGTTTATCTTCTGGAAAAAGCATCCTACATTTTATAATTTGGTTTTATCTCAAAATTTCCTTAAATTTAGGTATTGTCTTTCCTTTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate