Basic Information
VIS ID
TVIS30016182
Fusion event
HIV-LOC105374164 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
152898600/153180811 (Hg38)
End
152898373/153180811 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
LOC105374164
Nearest miRNA
hsa-let-7g/Upstream/1614816; hsa-mir-1224/Downstream/6101835;
Nearest TSS
ENST00000440867/Upstream/18541; ENST00000498457/Downstream/176296;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/17514, chr3-CpG: 131/Downstream/940187
Nearby gene
RAP2B(No orient, 12337)
Upstream sequence
ctcaaagtggggtcctggaaccagcagcatcagcagcactttgttaaatatgcagattctcaggtcccacctcagacttaatcagaaacactgagggtgg
Downstream sequence
ggactaataatttttaccctccaggtacttttattcatggtagtgtttgagaatcactgCTTGATGAGATATAGAAATAAAAACTTGTTATGGATGGTGG
Target sequence
tcctgagctcaagtgatctgcctgtttaggccttctaaagtgccgggattacaggcgtaagccattgcacctggccTCACACTGGAATTTTCTACGCACCTGATGAGGTATGCTTGTGGcagtggttctcaaagtggggtcctggaaccagcagcatcagcagcactttgttaaatatgcagattctcaggtcccacctcagacttaatcagaaacactgagggtgg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate