Basic Information
VIS ID
TVIS30016183
Fusion event
HIV-PHC3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.2
Reference genome
End
169873103/170155105 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7g/Upstream/1603156; hsa-mir-1224/Downstream/267998;
Nearest cancer related gene
PHC3(TSG, No orient, 0)
Upstream sequence
CTTCATATCTCAAGTCACACTCCACAAAGAAACTCACTTACTGAGCCCGATTACTGCAAGCTGTCTCCCCACTGACGCTAATTCTAGGAGTCACCAGAAA
Downstream sequence
TTTTGTGTCCACTGCTGAGTAAAAAGGCAGCAAAACAACATGTAGAGTATCATTCATATAGGTACATACAAATGTCTGTGTGTGTATATGTATCACAAAT
Target sequence
GAAACAAGTCTGCCAGAAAAAGCCACTTAACTCCCAACTACCTGTTAATGTCCTCAAAAGGAGTTTCCAACCGATTACTACCCATAGCCAAAGTCCATTTGAGAGTTGCCTCTACCGTTTCACTGATCAGAATCAATCAGGTATACCCTAAATAGAGAAACATTTCACATTAAAAGAATGATGTATCTGTATTCAGTGGCATTAAAAGAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate