Basic Information
VIS ID
TVIS30016184
Fusion event
HIV-chr3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.33
Reference genome
GRCh37/hg19
Start
182653272/182935484 (Hg38)
End
182653353/182935484 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA3C
Nearest miRNA
hsa-let-7g/Upstream/6420333; hsa-mir-1224/Downstream/951316;
Nearest TSS
ENST00000440867/Upstream/13546; ENST00000471731/Downstream/44667;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/140990, chr3-CpG: 91/Downstream/44477
Nearby gene
DCUN1D1(No orient, 7286)
Nearest cancer related gene
DCUN1D1(OG, No orient, 7286)
Upstream sequence
GCAATTGGCAATGGGAAATAGGTTGTGATCTCTGAAGAGATAAGGCTCTACCAGAAAAGATTAAACAGTCATCAGAGAAGATCCTGCCTAACAGAGCTTT
Downstream sequence
TGGCACTGGTGTCTTTAGACCAATGGACAGACTCTTCCTAGGCCTGGTTAAAGAGGAAGACATTCTCCAAAGCAGTTATACAAATTTACCGGGATCTCTC
Target sequence
AATAGCTAAACTGATAATTTGGATTTAGAACTTGAATTCCTTCCTACGCAACTTTGGGAACTTGCCTTCAAAGGCACATCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate