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TVIS30016187
Basic Information
VIS ID
TVIS30016187
Fusion event
HIV-VPS8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.2
Reference genome
GRCh37/hg19
Start
184690379/184972591 (Hg38)
End
184690037/184972591 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3C
Target gene
VPS8
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-6741-5p
;
hsa-mir-7977
;
hsa-mir-6748-5p
;
hsa-mir-876-3p
;
hsa-mir-323a-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-92a-2-5p
;
hsa-mir-654-5p
;
hsa-mir-541-3p
;
hsa-mir-3194-5p
;
hsa-mir-769-5p
;
hsa-mir-6761-5p
;
hsa-mir-665
;
hsa-mir-4768-3p
;
hsa-mir-6858-3p
;
hsa-mir-548s
;
hsa-mir-7156-3p
;
hsa-mir-642b-5p
;
hsa-mir-3926
;
hsa-mir-5189-3p
;
hsa-mir-3190-5p
;
hsa-mir-1184
;
hsa-mir-1208
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-4684-5p
;
hsa-mir-4786-5p
;
hsa-mir-6849-3p
;
hsa-mir-3675-3p
;
hsa-mir-6771-3p
;
hsa-mir-4482-3p
;
hsa-mir-7159-3p
;
hsa-mir-651-5p
;
hsa-mir-3187-3p
;
hsa-mir-4435
;
hsa-mir-588
;
hsa-mir-4701-5p
;
hsa-mir-6514-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6847-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-3934-5p
;
hsa-mir-383-3p
;
hsa-mir-6805-3p
;
hsa-mir-5691
;
hsa-mir-3194-3p
;
hsa-mir-9-5p
;
hsa-mir-6728-3p
;
hsa-mir-6800-3p
;
hsa-mir-2355-5p
;
hsa-mir-6787-5p
;
hsa-mir-663a
;
hsa-mir-1908-5p
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-744-5p
;
hsa-mir-6087
Nearest miRNA
hsa-let-7g/Upstream/731102; hsa-mir-1248/Downstream/280619;
Nearest TSS
ENST00000440867/Upstream/53535;
ENST00000488255/Downstream/9827;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/160124
,
chr3-CpG: 137/Downstream/179806
Upstream sequence
aaccttggttgcacactagagtcacctggggagctttgaacaattccagtactcaggctgcaccccagatcaattaaattaaagtctctggggatgaaac
Downstream sequence
ccagccaccaccatgttttaaagctcccttcatgattccaatgtgcagccaaggttggaaccactgCTATCACAGATCCCAGATGGCACAAAAGAAGAAA
Target sequence
AAGGCTTTATATTCATGGTTTGGCTGTGCTGCAAAACTTAAGGTGCATGAATGCTAGATGTGCCTGTTCTCTTTGGACTGAGATTTTGTGTATGCCATGTAGTTGCACCAGAGATAGGTCATCATTTATCATCGTCTCTATTCCCTGTGGTGAAAGTAGGCATGAAGAACTGGAGGAAAGCCCTCAAGGGCTACAGAGAAAGCTGAAGAAAGGTTAAAGAAGCCTATGGTGTACTAAttctcaaccttggttgca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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