Basic Information
VIS ID
TVIS30016192
Fusion event
HIV-ATP13A3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
194139841/194419112 (Hg38)
End
194139723/194419112 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATP13A3
miRNAs that regulate target gene
hsa-mir-590-3p ; hsa-mir-122-5p ; hsa-mir-103a-3p ; hsa-mir-98-5p ; hsa-mir-16-5p ; hsa-mir-150-5p ; hsa-mir-182-5p ; hsa-mir-340-5p ; hsa-mir-5692a ; hsa-mir-545-3p ; hsa-mir-3617-3p ; hsa-mir-3163 ; hsa-mir-34a-3p ; hsa-mir-551b-5p ; hsa-mir-4282 ; hsa-mir-455-5p ; hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-6516-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-5009-3p ; hsa-mir-5002-5p ; hsa-mir-5586-3p ; hsa-mir-583 ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-107 ; hsa-mir-4666a-3p ; hsa-mir-548c-3p ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-let-7g/Upstream/4589103; hsa-mir-3137/Downstream/715394;
Nearest TSS
ENST00000440867/Upstream/6049; ENST00000437597/Downstream/1272;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/20853, chr3-CpG: 118/Downstream/67631
Upstream sequence
gaaagacatgtaaaaatatgttcatagcagcaatatgttcagtaattatttaccaacagaggatggagaaatgaatttaatatattcctacaattgtata
Downstream sequence
ctatacagcaatgaaaataaaataatgtatcaacaaacaatgttgatgggagaatgcaagtcacagaaaaaagggaacaagataacattttcatgaagtt
Target sequence
TACTTACCCCCAtacactgaaagacatgtaaaaatatgttcatagcagcaatatgttcagtaattatttaccaacagaggatggagaaatgaatttaatatattcctacaattgtata
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate