Basic Information
VIS ID
TVIS30016198
Fusion event
HIV-PAK2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
End
196543751/196816629 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-500a-3p ; hsa-mir-193b-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-298 ; hsa-mir-922 ; hsa-mir-548e-5p ; hsa-mir-1253 ; hsa-mir-4311 ; hsa-mir-6838-5p ; hsa-mir-944 ; hsa-mir-3120-3p ; hsa-mir-3163 ; hsa-mir-4698 ; hsa-mir-5692a ; hsa-mir-8063 ; hsa-mir-3133 ; hsa-mir-3925-5p ; hsa-mir-8084 ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520e ; hsa-mir-520f-5p ; hsa-mir-519c-3p ; hsa-mir-520a-3p ; hsa-mir-519b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-519a-3p ; hsa-mir-302e ; hsa-mir-4799-5p ; hsa-mir-224-5p ; hsa-mir-218-5p ; hsa-mir-1273e ; hsa-mir-636 ; hsa-mir-648 ; hsa-mir-4773 ; hsa-mir-595 ; hsa-mir-658 ; hsa-mir-219b-3p ; hsa-mir-6840-3p ; hsa-mir-7846-3p ; hsa-mir-302f ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-625-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-4786-5p ; hsa-mir-4307 ; hsa-mir-6502-3p ; hsa-mir-6512-5p ; hsa-mir-4646-3p ; hsa-mir-4433b-5p ; hsa-mir-580-3p ; hsa-mir-1287-3p ; hsa-mir-7976 ; hsa-mir-4766-5p ; hsa-mir-345-3p ; hsa-mir-6779-3p ; hsa-mir-4687-5p ; hsa-mir-129-1-3p ; hsa-mir-129-2-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-134-5p ; hsa-mir-137 ; hsa-mir-1273g-3p ; hsa-mir-3160-3p ; hsa-mir-4487 ; hsa-mir-4793-3p ; hsa-mir-558 ; hsa-mir-5694 ; hsa-mir-668-3p ; hsa-mir-6890-3p ; hsa-mir-7703 ; hsa-mir-96-3p
Nearest miRNA
hsa-let-7g/Upstream/934234; hsa-mir-4797/Downstream/477249;
Upstream sequence
TGTGCCAGAACTTTTAAACTGTGACGAGTTTGTTTCTATTTATTTGTACAAGTATTTTCTGGAGCTTTGAATCTGATGATTGCCTGGTAAATGTATTGCG
Downstream sequence
TTATTCTTGCATCATTCATGTCCAAGTTGTAGATACAGCTTAATATAAAATCGGGCACTGAAGAACATCTTCTTTCTGATGAACAGCTAAGTGGAACCAG
Target sequence
GTAACACCCAATTTATCTGTTTTTCCTTGAATGAATAGTAGAAGATTTTGGATGAGATTTTTAGTTGTACAGACTTTGTTCTCCTCTGATGGGAGTAAGAAATAAAAGCACAGCTAACTTACACCCGTAGTTCAAAAACACAAGAGTGAGCAGATTTTTAAAACGTCATCTCGTTCTCGTTTGTAAGGAAAGGAGTAGTTTACCCCCACTTTGTGACTCAGTGCTCTCTGAAATATGGCATAAGAGGAAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate