Basic Information
VIS ID
TVIS30016208
Fusion event
HIV-ZNF718 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
135174/141392 (Hg38)
End
134965/141392 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF718
Nearest miRNA
hsa-mir-12113/Downstream/208765;
Nearest TSS
ENST00000502981/Upstream/16854; ENST00000503699/Downstream/154763;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/16433, chr4-CpG: 49/Downstream/71196
Upstream sequence
aaaatgtgggaaaagtttaaatcataaaatattttttaaaccctgataaagaattggagacgtttggctaattaaacattttcataaagctgttagtttt
Downstream sequence
gattaaagtaaaataaaaagtattgtaaaaatgcatcagcagtttggcaattatttttttaaatatagttaagcatgaagctggatataatgtaaagcca
Target sequence
aaaaaaagagaatagttttgtctaattcaatagttatctaaaagttggttcaaattacagatttaaaaaggttattcataaaacaatgtagtaaggaatcattaggcaaaaaatgtgggaaaagtttaaatcataaaatattttttaaaccctgataaagaattggagacgtttggctaattaaacattttcataaagctgttagtttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate