Basic Information
VIS ID
TVIS30016212
Fusion event
HIV-SLC26A1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
980310/986522 (Hg38)
End
980423/986522 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC26A1
Nearest miRNA
hsa-mir-571/Upstream/636270; hsa-mir-12113/Downstream/999862;
Nearest TSS
ENST00000502981/Upstream/12966; ENST00000509744/Downstream/373;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/12173, chr4-CpG: 55/Downstream/4616
Upstream sequence
gtagtttaaatcaagattacttatagtccctaaaacaatgtaaatgctctgtaaatagctgttatactgtattgttttaaaatatgtattatttcgtatt
Downstream sequence
CGCACGCTTtactcaggaggctggggtgagaaaatcgctgaagccccggagatggaggttgcagtgagctgagatcgcgccactgcacctcagcctgggc
Target sequence
gctttggctttaaaacaatattttcagtctgcttggttgaatccatggatctgaagccaagtgtaaggagggccCAGTGTGCTCTTCTGGGGTAATTCTCCTTCCTGCTAAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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