Basic Information
VIS ID
TVIS30016216
Fusion event
HIV-KCNIP4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.31
Reference genome
GRCh37/hg19
Start
20732380/20730757 (Hg38)
End
20732126/20730757 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
KCNIP4
Nearest miRNA
hsa-mir-12113/Upstream/202373; hsa-mir-12115/Downstream/733943;
Nearest TSS
ENST00000502981/Upstream/17681; ENST00000610199/Downstream/36051;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/30044, chr4-CpG: 95/Downstream/1217705
Upstream sequence
CATGGCCTGAAGGAGCCTTTAAAAATGAATGGTCTCTCAATTACAGAGAAAGAATTGGGGAGCAGAAACCACTGCTCAGTGGCTGTGTTCAGTTTAGCAT
Downstream sequence
ATTCTTTAGAAATGAGTTAGGGGACAGACTTTGGGCATTATTGGAGCACTTGTCAGTTGCATGTGAATAGCACTTACTGAGCTGTTTATGGTAGTGGTAA
Target sequence
AGACTTTTATACAGGTACAAGGAAAATTTGTGTGTATGAGCCAGCAGTTCATGAAGATTGGAGGCTGGCGCATAGGAGGCAGGGTGGTGGATTAAGAGGTAACATGTTTGCAGTAATCATCTCTCTTTCTGTCTGCTAGTTATGGCTAAAGCTGCATGGCCTGAAGGAGCCTTTAAAAATGAATGGTCTCTCAATTACAGAGAAAGAATTGGGGAGCAGAAACCACTGCTCAGTGGCTGTGTTCAGTTTAGCAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate