Basic Information
VIS ID
TVIS30016221
Fusion event
HIV-LOC439933 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
GRCh37/hg19
Start
36275803/36274181 (Hg38)
End
36275832/36274181 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC439933
Nearest miRNA
hsa-mir-12113/Upstream/7454513; hsa-mir-1243/Downstream/152185;
Nearest TSS
ENST00000502981/Upstream/17663; ENST00000506008/Downstream/7441;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/29414, chr4-CpG: 173/Downstream/969447
Nearby gene
DTHD1(No orient, 7440)
Upstream sequence
ggaaatttgaacctgaccacatttttgtgatattaaggaattttattaattattttctaggtgggggaatgatatgatgatattcttaaaataatGTGTG
Downstream sequence
AATCATCAAACATTTGTTGACCTTCTGCTGTATCTAGAGCTCTGTGATCGGGATGAAGTATGAGATATTAAGCCATTACCAGGTGGTAGTTACTCTACCT
Target sequence
GATTGTTTATTACATTTCAACATTTTCTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate