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TVIS30016227
Basic Information
VIS ID
TVIS30016227
Fusion event
HIV-TXK integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p12
Reference genome
GRCh37/hg19
Start
48115976/48113959 (Hg38)
End
48116092/48113959 (Hg38)
Orient
+
Location type
Intronic
Target gene
TXK
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-340-5p
;
hsa-mir-503-3p
;
hsa-mir-6861-5p
;
hsa-mir-186-3p
;
hsa-mir-382-3p
;
hsa-mir-3159
;
hsa-mir-541-5p
;
hsa-mir-551b-5p
;
hsa-mir-619-5p
;
hsa-mir-6807-5p
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-1287-5p
;
hsa-mir-3135b
;
hsa-mir-6778-3p
;
hsa-mir-6839-5p
;
hsa-mir-378j
;
hsa-mir-150-5p
;
hsa-mir-7107-5p
;
hsa-mir-1234-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-6504-3p
;
hsa-mir-512-3p
;
hsa-mir-4438
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-6878-3p
;
hsa-mir-3156-3p
;
hsa-mir-1260b
;
hsa-mir-1260a
;
hsa-mir-188-3p
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-5589-5p
;
hsa-mir-4731-5p
;
hsa-mir-212-5p
;
hsa-mir-1224-3p
;
hsa-mir-141-5p
;
hsa-mir-101-5p
;
hsa-mir-6813-3p
;
hsa-mir-1976
;
hsa-mir-23a-5p
;
hsa-mir-23b-5p
;
hsa-mir-3653-5p
;
hsa-mir-4279
;
hsa-mir-4722-3p
;
hsa-mir-4740-3p
;
hsa-mir-498
;
hsa-mir-5089-5p
;
hsa-mir-5571-5p
;
hsa-mir-6506-5p
;
hsa-mir-6727-3p
;
hsa-mir-6747-3p
Nearest miRNA
hsa-mir-12113/Upstream/461216; hsa-mir-1243/Downstream/4598723;
Nearest TSS
ENST00000502981/Upstream/33781;
ENST00000506375/Downstream/586;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/96537
,
chr4-CpG: 49/Downstream/155386
Upstream sequence
acataaatcttttagcatagtatctgatatacaggaagctcctgttaaatgttagctttTTCTGTTAACATGCTGCCTTGGATTTAATTCTTACAGAGTC
Downstream sequence
catacatgaaataaaaattaagtggagaacaatgccgcacacggtgggaatgcaatggaatgaacaatgaaatctaaaggatcaggaaaggatcccagat
Target sequence
ATTTACTGCCACCAAAGTATAAGATACACCGGTAgttttggggagatagataactaagataggattcttgcccttaaagggaaaaaatacgtattggagcacagacctataaacaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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