Basic Information
VIS ID
TVIS30016228
Fusion event
HIV-TEC integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p12
Reference genome
GRCh37/hg19
Start
48176597/48174580 (Hg38)
End
48176622/48174580 (Hg38)
Orient
+
Location type
Intronic
Target gene
TEC
Nearest miRNA
hsa-mir-12113/Upstream/521837; hsa-mir-1243/Downstream/4538102;
Nearest TSS
ENST00000502981/Upstream/18714; ENST00000506375/Downstream/54079;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/157158, chr4-CpG: 49/Downstream/94765
Nearest cancer related gene
TEC(OG, No orient, 0)
Upstream sequence
aaaccctgtctctactaaaaatacaaaaattagccaggcatggtggtatatgcctataatcccagctacttgggtggctgaggcatgagaatcgcttgaa
Downstream sequence
ctgagatcataccactgcactccagcctgggtgacaaaggaagactccatctcaaaggaaaaaaaaaaaaagaaGTGTGGTAGGAATGGTTCTCTGCTAA
Target sequence
cctgggaagtggaggtctcagtgag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate