Basic Information
VIS ID
TVIS30016231
Fusion event
HIV-REST integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
End
57776765/56910542 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-21-5p ; hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-302e ; hsa-mir-4690-5p ; hsa-mir-4742-5p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-6835-3p ; hsa-mir-142-5p ; hsa-mir-190a-3p ; hsa-mir-4693-5p ; hsa-mir-4796-3p ; hsa-mir-5590-3p ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-620 ; hsa-mir-670-5p ; hsa-mir-548l ; hsa-mir-1270 ; hsa-mir-4319 ; hsa-mir-4324 ; hsa-mir-4251 ; hsa-mir-4531 ; hsa-mir-4683 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-105-5p ; hsa-mir-4719 ; hsa-mir-7853-5p ; hsa-mir-562 ; hsa-mir-646 ; hsa-mir-548n ; hsa-mir-4323 ; hsa-mir-3653-3p ; hsa-mir-4660 ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-4802-3p ; hsa-mir-4422 ; hsa-mir-4752 ; hsa-mir-6833-5p ; hsa-mir-7847-3p ; hsa-mir-539-5p ; hsa-mir-4638-3p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-548c-3p ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-378f ; hsa-mir-378h ; hsa-mir-378i ; hsa-mir-378e ; hsa-mir-378c ; hsa-mir-422a ; hsa-mir-378d ; hsa-mir-9-3p ; hsa-mir-5703 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-494-3p ; hsa-mir-7844-5p ; hsa-mir-6083 ; hsa-mir-676-5p ; hsa-mir-302a-5p ; hsa-mir-421 ; hsa-mir-7159-5p ; hsa-mir-138-2-3p ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-505-3p ; hsa-mir-4668-5p ; hsa-mir-6769a-3p ; hsa-mir-3943 ; hsa-mir-410-3p
Nearest miRNA
hsa-mir-12113/Upstream/4197795; hsa-mir-1243/Downstream/4012077;
Upstream sequence
TTGCAGTAGACTATTGGGAATTAACAACTATTTTAAAGATTTGTTTTTAATAGGCGATGAAGTTTACTGAGTTATAAAGATCATACTGGAAAATTTTTAA
Downstream sequence
TGCTCTTGTTTTGTTTTGTTTTTAATTCAGAATACAGTTATGGCCACCCAGGTAATGGGGCAGTCTTCTGGAGGAGGAGGGCTGTTTACCAGCAGTGGCA
Target sequence
GTTATGAAGAATTACAGCGATGTGGTTTTAAGCCAGTAACAGTAGTGTTTAAACTGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate