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TVIS30016234
Basic Information
VIS ID
TVIS30016234
Fusion event
HIV-BMP2K integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37/hg19
Start
79720629/78799475 (Hg38)
End
79720885/78799475 (Hg38)
Orient
+
Location type
Intronic
Target gene
BMP2K
miRNAs that regulate target gene
hsa-mir-192-5p
;
hsa-mir-98-5p
;
hsa-let-7e-5p
;
hsa-mir-1228-3p
;
hsa-mir-190a-3p
;
hsa-mir-5011-5p
;
hsa-mir-1277-5p
;
hsa-mir-6885-3p
;
hsa-mir-6771-3p
;
hsa-mir-1909-5p
;
hsa-mir-4693-3p
;
hsa-mir-551b-5p
;
hsa-mir-4311
;
hsa-mir-548c-3p
;
hsa-mir-4477a
;
hsa-mir-508-5p
;
hsa-mir-3145-5p
;
hsa-mir-606
;
hsa-mir-5582-3p
;
hsa-mir-548f-3p
;
hsa-mir-548e-3p
;
hsa-mir-548az-3p
;
hsa-mir-548ar-3p
;
hsa-mir-548a-3p
;
hsa-mir-4672
;
hsa-mir-466
;
hsa-mir-3941
;
hsa-mir-610
;
hsa-mir-4643
;
hsa-mir-4789-3p
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-5697
;
hsa-mir-101-5p
;
hsa-mir-8062
;
hsa-mir-8079
;
hsa-mir-1245a
Nearest miRNA
hsa-mir-12113/Upstream/2223849; hsa-mir-1243/Downstream/3953862;
Nearest TSS
ENST00000502981/Upstream/23097;
ENST00000515075/Downstream/51417;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/22671
,
chr4-CpG: 68/Downstream/139584
Upstream sequence
TTATATTCGTTGATTTCTTATAATGTTTACAATTTGAAATTGGCATACAGGTTTTGTATTTTAGTTACTTAAATGTTTTTCATAGTGGTTATAGGTATTT
Downstream sequence
ACAGtgatatgctataaatgggttataggtgtaccaagatttgatttttcctttcaccccctcagagtagcctggttgtggttgaaggtccctgcctgcc
Target sequence
ATAATCAGCATGAAAATATTAGAAAGTGAAAGTGTATAAGAATTTGTGTTTTTAGCTTACATACAAATGGAGATCCTGCTGTGGATTCAAATGTGTGTATTTGTGTATGTAATTAGAGTTTTACATCCAAGTTTTATCTTAGTATGATTTGGCTTTTGTATCAAAAGTACGTAAGATGTTTGTAAGGCTGTGTCTAGACTTATCTCTGAGTATCAGAATAATCTGACTAAATCTTGCTTACTCATGTGCTATGGT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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