Basic Information
VIS ID
TVIS30016235
Fusion event
HIV-chr4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.21
Reference genome
GRCh37/hg19
Start
82411700/81490546 (Hg38)
End
82411938/81490546 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/4914920; hsa-mir-1243/Downstream/1262791;
Nearest TSS
ENST00000502981/Upstream/18618; ENST00000609552/Downstream/553523;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/18274, chr4-CpG: 73/Downstream/553471
Nearby gene
RASGEF1B(No orient, 18639)
Upstream sequence
GATCCAGCATTGGCAATCACTTTGAACATCAGGGGTTTTTCCTGTATAAGCAGGAATTATTTATAGCCATACAAATTAAATTTCAGGGAAGGTGGGGTGG
Downstream sequence
gataccaaagattatgttctttgtatgacaaggaggacacagtctatggagcagacacataaataattaggtgaatttgcattgtaataagtgctgtaac
Target sequence
GTAGGGaatgactaacattattgagcactatatgtatgtatatatgtatatgccagggattgtgctaagtactttccacatatatttatgtcatctgcataacaatccctatgcagcatctagtagtatctctatcttcacagaagagaaacctgaagctcagaaaaagtgtttataaattgcttaagaacaaatatctaataaattacaaagccaagatttggacccagctgggcct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate