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TVIS30016239
Basic Information
VIS ID
TVIS30016239
Fusion event
HIV-UBE2D3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q24
Reference genome
GRCh37/hg19
Start
103728896/102807739 (Hg38)
End
103728834/102807739 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBE2D3
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-101-3p
;
hsa-mir-98-5p
;
hsa-let-7b-5p
;
hsa-mir-877-3p
;
hsa-mir-423-5p
;
hsa-mir-218-5p
;
hsa-mir-136-5p
;
hsa-mir-6126
;
hsa-mir-6864-5p
;
hsa-mir-920
;
hsa-mir-6726-5p
;
hsa-mir-5591-5p
;
hsa-mir-4300
;
hsa-mir-3934-3p
;
hsa-mir-3670
;
hsa-mir-539-5p
;
hsa-mir-493-3p
;
hsa-mir-4635
;
hsa-mir-3664-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-4453
;
hsa-mir-4538
;
hsa-mir-6854-5p
;
hsa-mir-5003-3p
;
hsa-mir-6833-5p
;
hsa-mir-7847-3p
;
hsa-mir-3190-3p
;
hsa-mir-6894-5p
;
hsa-mir-765
;
hsa-mir-7154-3p
;
hsa-mir-766-5p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-4795-5p
;
hsa-mir-4657
;
hsa-mir-4491
;
hsa-mir-4519
;
hsa-mir-301b-3p
;
hsa-mir-130b-3p
;
hsa-mir-301a-3p
;
hsa-mir-3666
;
hsa-mir-4295
;
hsa-mir-454-3p
;
hsa-mir-130a-3p
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-152-3p
;
hsa-mir-148b-3p
;
hsa-mir-148a-3p
;
hsa-mir-188-3p
;
hsa-mir-195-3p
;
hsa-mir-4733-5p
;
hsa-mir-16-2-3p
;
hsa-mir-577
;
hsa-mir-888-5p
;
hsa-mir-376c-3p
;
hsa-mir-421
;
hsa-mir-7159-5p
;
hsa-mir-676-5p
;
hsa-mir-505-3p
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-769-5p
;
hsa-mir-4786-5p
;
hsa-mir-664a-5p
;
hsa-mir-4794
;
hsa-mir-7162-3p
;
hsa-mir-544b
;
hsa-mir-6849-3p
;
hsa-mir-6771-3p
;
hsa-mir-1245b-3p
;
hsa-mir-1249-5p
;
hsa-mir-1257
;
hsa-mir-1321
;
hsa-mir-1343-5p
;
hsa-mir-30a-5p
;
hsa-mir-30b-5p
;
hsa-mir-30c-5p
;
hsa-mir-30d-5p
;
hsa-mir-30e-5p
;
hsa-mir-3607-5p
;
hsa-mir-3613-3p
;
hsa-mir-4330
;
hsa-mir-4419a
;
hsa-mir-4510
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-4790-3p
;
hsa-mir-4802-5p
;
hsa-mir-551b-5p
;
hsa-mir-6081
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-6130
;
hsa-mir-6133
;
hsa-mir-6515-5p
;
hsa-mir-6783-5p
;
hsa-mir-6797-5p
;
hsa-mir-6799-5p
;
hsa-mir-6824-5p
;
hsa-mir-939-5p
;
hsa-mir-942-5p
Nearest miRNA
hsa-mir-12113/Upstream/1477325; hsa-mir-1243/Downstream/6680959;
Nearest TSS
ENST00000502981/Upstream/5045;
ENST00000501133/Downstream/2214;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/46548
,
chr4-CpG: 130/Downstream/18735
Upstream sequence
AAAAAGTTCAGCAAGGAATAGCCATCACCTGAAATATATATTTAAAAAATGAAAAAAGGTAAATGTTTTCTCAAAATAACAGCAAATTAAGTAAACTGCT
Downstream sequence
AAAAAATCTGTCAGAATAAGCAACACCATTCTCTAAAAAAATTACTACCATACACTCATCATTCATGTTTCCTTTTGATTGTCTATAGGTATGTTCCTTG
Target sequence
TATTTAAAAAATGAAAAAAGGTAAATGTTTTCTCAAAATAACAGCAAATTAAGTAAACTGCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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