Basic Information
VIS ID
TVIS30016239
Fusion event
HIV-UBE2D3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q24
Reference genome
End
103728834/102807739 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-101-3p ; hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-218-5p ; hsa-mir-136-5p ; hsa-mir-6126 ; hsa-mir-6864-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-3934-3p ; hsa-mir-3670 ; hsa-mir-539-5p ; hsa-mir-493-3p ; hsa-mir-4635 ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4453 ; hsa-mir-4538 ; hsa-mir-6854-5p ; hsa-mir-5003-3p ; hsa-mir-6833-5p ; hsa-mir-7847-3p ; hsa-mir-3190-3p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4795-5p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-4519 ; hsa-mir-301b-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-130a-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-188-3p ; hsa-mir-195-3p ; hsa-mir-4733-5p ; hsa-mir-16-2-3p ; hsa-mir-577 ; hsa-mir-888-5p ; hsa-mir-376c-3p ; hsa-mir-421 ; hsa-mir-7159-5p ; hsa-mir-676-5p ; hsa-mir-505-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-7162-3p ; hsa-mir-544b ; hsa-mir-6849-3p ; hsa-mir-6771-3p ; hsa-mir-1245b-3p ; hsa-mir-1249-5p ; hsa-mir-1257 ; hsa-mir-1321 ; hsa-mir-1343-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3607-5p ; hsa-mir-3613-3p ; hsa-mir-4330 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4790-3p ; hsa-mir-4802-5p ; hsa-mir-551b-5p ; hsa-mir-6081 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6515-5p ; hsa-mir-6783-5p ; hsa-mir-6797-5p ; hsa-mir-6799-5p ; hsa-mir-6824-5p ; hsa-mir-939-5p ; hsa-mir-942-5p
Nearest miRNA
hsa-mir-12113/Upstream/1477325; hsa-mir-1243/Downstream/6680959;
Upstream sequence
AAAAAGTTCAGCAAGGAATAGCCATCACCTGAAATATATATTTAAAAAATGAAAAAAGGTAAATGTTTTCTCAAAATAACAGCAAATTAAGTAAACTGCT
Downstream sequence
AAAAAATCTGTCAGAATAAGCAACACCATTCTCTAAAAAAATTACTACCATACACTCATCATTCATGTTTCCTTTTGATTGTCTATAGGTATGTTCCTTG
Target sequence
TATTTAAAAAATGAAAAAAGGTAAATGTTTTCTCAAAATAACAGCAAATTAAGTAAACTGCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate