Basic Information
VIS ID
TVIS30016250
Fusion event
HIV-NUDT6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q28.1
Reference genome
GRCh37/hg19
Start
123819447/122898292 (Hg38)
End
123819317/122898292 (Hg38)
Orient
-
Location type
Intronic
Target gene
NUDT6
Nearest miRNA
hsa-mir-12113/Upstream/8241438; hsa-mir-1305/Downstream/2608967;
Nearest TSS
ENST00000502981/Upstream/5604; ENST00000422835/Downstream/14996;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/70467, chr4-CpG: 48/Downstream/23915
Upstream sequence
GTAGTATGAATAAAATTGATTAGTTTGTGTTTTCTTGTCTCCCATTTCTTTGTGTCTTCTTGTCTATGAATTCTTTTTTCTTTTTTTTTGTTGGGGAGGG
Downstream sequence
GCAGGTGGAAAGATCTGATCTTGGAATAGGGATAAATATAGAAAAATGGATTAAAAACAATTATGAGATGACATGGACAATATTCTTATGGCTGACATGA
Target sequence
TTTATGTAAAAATGTAATTGCTTTTCATGAGTAGTATGAATAAAATTGATTAGTTTGTGTTTTCTTGTCTCCCATTTCTTTGTGTCTTCTTGTCTATGAATTCTTTTTTCTTTTTTTTTGTTGGGGAGGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate