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TVIS30016254
Basic Information
VIS ID
TVIS30016254
Fusion event
HIV-SLC10A7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.22
Reference genome
GRCh37/hg19
Start
147393213/146472061 (Hg38)
End
147393395/146472061 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC10A7
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-196a-5p
;
hsa-let-7d-5p
;
hsa-mir-484
;
hsa-mir-106b-5p
;
hsa-mir-218-5p
;
hsa-mir-192-3p
;
hsa-mir-4799-5p
;
hsa-mir-5189-3p
;
hsa-mir-6803-5p
;
hsa-mir-6751-5p
;
hsa-mir-7109-5p
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-3935
;
hsa-mir-6846-5p
;
hsa-mir-6848-5p
;
hsa-mir-4697-5p
;
hsa-mir-4488
;
hsa-mir-1237-5p
;
hsa-mir-6816-5p
;
hsa-mir-3196
;
hsa-mir-3180-3p
;
hsa-mir-3180
;
hsa-mir-6787-5p
;
hsa-mir-663a
;
hsa-mir-1908-5p
;
hsa-mir-4749-5p
;
hsa-mir-4706
;
hsa-mir-4259
;
hsa-mir-6831-5p
;
hsa-mir-3927-3p
;
hsa-mir-577
;
hsa-mir-382-5p
;
hsa-mir-495-5p
;
hsa-let-7c-5p
;
hsa-let-7e-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-let-7f-5p
;
hsa-let-7g-5p
;
hsa-mir-4458
;
hsa-mir-4500
;
hsa-let-7i-5p
;
hsa-mir-98-5p
;
hsa-mir-222-3p
;
hsa-mir-221-3p
;
hsa-mir-548v
;
hsa-mir-187-5p
;
hsa-mir-3121-5p
;
hsa-mir-1306-5p
;
hsa-mir-6507-3p
;
hsa-mir-5089-3p
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-181d-5p
;
hsa-mir-181c-5p
;
hsa-mir-181a-5p
;
hsa-mir-181b-5p
;
hsa-mir-132-3p
;
hsa-mir-212-3p
;
hsa-mir-3177-5p
;
hsa-mir-4282
;
hsa-mir-4302
;
hsa-mir-6856-3p
Nearest miRNA
hsa-mir-12113/Upstream/63373; hsa-mir-1305/Downstream/872568;
Nearest TSS
ENST00000502981/Upstream/230255;
ENST00000281321/Downstream/31842;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/295651
,
chr4-CpG: 84/Downstream/49878
Upstream sequence
ATTTCCTGTTCTCCATACCCCCCCACTCCCAAAAGATAGCTCATGCAGTTTTCCAAATATACACTAAAAATAAAGAGAAATAAAAGTGACATCTCAATAC
Downstream sequence
AGAAAAACACTTCCATGTACGGCATACATACCAGTGTTAGGAAGAAAAACAAACCCAGAAATTAATTAAGAAATGGGTGGTTTTACAGAGTGCTATAAGA
Target sequence
AAAATATAAATCCTTCAGCATCTTAAAAATAAACTTTTCTATAAAATATAGTGGAATAACTGAGGGACAAACATTAAAGAATAATGAACGTGCAAAAAAAATGCACTGCTGTCAGCATTATACCTGGGTACAAATGTGTTAGAGCATCTTAGTTTAAAACAAATCAAGTTAAGCGCCTGTTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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